Our Featured Research Page lists cancer prevention, treatment and quality of life studies enrolling people with or at high risk for hereditary cancers. Sign up for our community newsletter to stay up to date on the latest hereditary cancer research.
Featured Studies Results
Research Study on the Genetics of Breast Cancer
Surveys, Registries, Interviews
This population-based research study aims to enroll at least 10,000 people aged 18 and older who live in the United States. A diagnosis of cancer is NOT required. Participants may receive information about their genetic ancestry for free.
Pancreatic Cancer Screening Study (CAPS5)
Clinicaltrials.gov identifier:
NCT02000089
Prevention
Screening study for people at high risk for pancreatic cancer
Vaccines for Pancreatic Cancer After Chemotherapy and Prior to Surgery
Clinicaltrials.gov identifier:
NCT05111353
Treatment
Vaccine study for people diagnosed with pancreatic cancer
Ethical Challenges and Best Practices in End-of-Life Care
Surveys, Registries, Interviews
Interview of palliative care patients and/or their adult family members who have been offered and involved in genetic testing or counseling
Effectiveness of Lymph Node Mapping to Reduce the Risk of Swelling in the Legs in Patients with Stage I Endometrial Cancer
Clinicaltrials.gov identifier:
NCT05646316
Treatment
People with stage I endometrial cancer who are having a hysterectomy
Roadmap to Parenthood: A Study about Fertility and Family-Building After Cancer
Clinicaltrials.gov identifier:
NCT06050135
Surveys, Registries, Interviews
A survey for people aged 18-45, assigned female at birth, and history of a cancer diagnosis
Registry to Discover New Treatments and Developmental Processes of Colorectal and Endometrial Cancer in Patients with Hereditary Cancer
Clinicaltrials.gov identifier:
NCT06096688
Surveys, Registries, Interviews
Study to collect and save data, cancer samples, and cancer family health histories from people who screen for colorectal endometrial cancer
Exploring the Attitudes of Those Who Tested Positive for an Adult-Onset Cancer Predisposition as a Minor
Surveys, Registries, Interviews
Survey and interview for people who tested positive for an adult-onset cancer predisposition as a minor
ShareForCures®: Susan G. Komen's People-Powered, Data-Driven Breast Cancer Research Registry
Clinicaltrials.gov identifier:
NCT05654246
Surveys, Registries, Interviews
Registry for anyone diagnosed with breast cancer
Exploring How People of Caribbean Descent Share Information About Their Genetic Mutations with Family Members
Surveys, Registries, Interviews
Survey and interview for people of Caribbean descent who tested positive for a genetic mutation linked to cancer.
Treatment of HER2-positive Colorectal Cancer as First Line Treatment in the Metastatic Setting
Clinicaltrials.gov identifier:
NCT05253651
Treatment
People with HER2-positive colorectal cancer who have not yet received treatment in the metastatic setting
Study of Colorectal Cancer and Genetics in Hispanic and Latino People (ENLACE Study)
Treatment
Hispanic and Latino people diagnosed with colorectal cancer
Pancreatic Cancer Early Detection for People at High Risk
Clinicaltrials.gov identifier:
NCT04970056
Prevention
Registry and biobank for high risk people undergoing pancreatic cancer screening
My Best GI Eating Study
Clinicaltrials.gov identifier:
NCT05396846
Prevention
Diet and weight loss study for people who are overweight and at increased risk of colorectal cancer
Registry to Promote Health Equity for People of African Ancestry with Breast or Prostate Cancer
Clinicaltrials.gov identifier:
NCT05754658
Surveys, Registries, Interviews
This is a registry for people of African ancestry who have breast or prostate cancer
A Surveillance Program for Women at High Risk for Breast Cancer (CAPSBRACA)
Clinicaltrials.gov identifier:
NCT03729115
Surveys, Registries, Interviews
Screening study for women at risk for breast cancer due to an inherited mutation or other risk factor
Nipple Sparing Mastectomy With Immediate Implant-Based Reconstruction for Women With Early-Stage Breast Cancer
Clinicaltrials.gov identifier:
NCT05720039
Treatment
Nipple sparing mastectomy with reconstruction for women with early-stage breast cancer
Survey about Motivations and Barriers to Talking with Family Members about Inherited Cancer Risk
Surveys, Registries, Interviews
Survey for people with an inherited gene mutation
Breastfeeding and Breast Cancer Screening in People at High Risk: Knowledge and Perspectives
Surveys, Registries, Interviews
Online survey for women with an ATM, BARD1, BRCA1, BRCA2, CDH1, CHEK2, PALB2, PTEN, RAD51C, RAD51D, STK11 or TP53 inherited mutation.
Tools To Be Fit: Tools to Improve Nutrition and Physical Activity for Cancer Survivors
Clinicaltrials.gov identifier:
NCT05056077
Quality of Life
Bladder, breast, colon, endometrial, kidney (renal cell carcinoma), ovarian, prostate, or rectal cancer
Blood Markers of Early Pancreas Cancer
Clinicaltrials.gov identifier:
NCT03568630
Prevention
Observational study for people with family history of pancreas cancer or an inherited mutation linked to pancreatic cancer risk
Helping Latinas Understand Their Risk for Breast Cancer and Get Breast Cancer Care
Clinicaltrials.gov identifier:
NCT05483283
Prevention
Latinas with a high risk of breast cancer
Bazedoxifene Plus Conjugated Estrogens for Hot Flashes in Women at High Risk for Breast Cancer
Clinicaltrials.gov identifier:
NCT04821141
Quality of Life
Women at high risk for breast cancer due to ATM, CDH1, CHEK2, NBN, NF1, PALB2, PTEN, STK11, P53 or PTEN mutation who have hot flashes
Inherited Cancer Registry (ICARE): Contribute to Research While Staying Informed
Clinicaltrials.gov identifier:
NCT03231891
Surveys, Registries, Interviews
People with an inherited mutation or cancer in the family
ELLIE's Project
Quality of Life
A survey to gain a better understanding of the baseline lifestyle factors related to nutrition and physical activity in people with a hereditary cancer gene mutation.
If you would like a more in-depth search, visit our In-Depth Search Tool that searches for studies in FORCE’s database and in clinicaltrials.gov