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Our Featured Research Page lists cancer prevention, treatment and quality of life studies enrolling people with or at high risk for hereditary cancers. Sign up for our community newsletter to stay up to date on the latest hereditary cancer research.

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Featured Studies Results

Research Study on the Genetics of Breast Cancer

Research Study on the Genetics of Breast Cancer

Surveys, Registries, Interviews
This population-based research study aims to enroll at least 10,000 people aged 18 and older who live in the United States. A diagnosis of cancer is NOT required. Participants may receive information about their genetic ancestry for free.

Pancreatic Cancer Screening Study (CAPS5)

Pancreatic Cancer Screening Study (CAPS5)

Clinicaltrials.gov identifier:
NCT02000089

Prevention
Screening study for people at high risk for pancreatic cancer

Vaccines for Pancreatic Cancer  After Chemotherapy and Prior to Surgery

Vaccines for Pancreatic Cancer After Chemotherapy and Prior to Surgery

Clinicaltrials.gov identifier:
NCT05111353

Treatment
Vaccine study for people diagnosed with pancreatic cancer

Ethical Challenges and Best Practices in End-of-Life Care

Ethical Challenges and Best Practices in End-of-Life Care

Surveys, Registries, Interviews
Interview of palliative care patients and/or their adult family members who have been offered and involved in genetic testing or counseling

Effectiveness of Lymph Node Mapping to Reduce the Risk of Swelling in the Legs in Patients with Stage I Endometrial Cancer

Effectiveness of Lymph Node Mapping to Reduce the Risk of Swelling in the Legs in Patients with Stage I Endometrial Cancer

Clinicaltrials.gov identifier:
NCT05646316

Treatment
People with stage I endometrial cancer who are having a hysterectomy

Roadmap to Parenthood: A Study about Fertility and Family-Building After Cancer

Roadmap to Parenthood: A Study about Fertility and Family-Building After Cancer

Clinicaltrials.gov identifier:
NCT06050135

Surveys, Registries, Interviews
A survey for people aged 18-45, assigned female at birth, and history of a cancer diagnosis

Registry to Discover New Treatments and Developmental Processes of Colorectal and Endometrial Cancer in Patients with Hereditary Cancer

Registry to Discover New Treatments and Developmental Processes of Colorectal and Endometrial Cancer in Patients with Hereditary Cancer

Clinicaltrials.gov identifier:
NCT06096688

Surveys, Registries, Interviews
Study to collect and save data, cancer samples, and cancer family health histories from people who screen for colorectal endometrial cancer

Exploring the Attitudes of Those Who Tested Positive for an Adult-Onset Cancer Predisposition as a Minor

Exploring the Attitudes of Those Who Tested Positive for an Adult-Onset Cancer Predisposition as a Minor

Surveys, Registries, Interviews
Survey and interview for people who tested positive for an adult-onset cancer predisposition as a minor

ShareForCures®: Susan G. Komen's People-Powered, Data-Driven Breast Cancer Research Registry

ShareForCures®: Susan G. Komen's People-Powered, Data-Driven Breast Cancer Research Registry

Clinicaltrials.gov identifier:
NCT05654246

Surveys, Registries, Interviews
Registry for anyone diagnosed with breast cancer

Exploring How People of Caribbean Descent Share Information About Their  Genetic Mutations with  Family Members

Exploring How People of Caribbean Descent Share Information About Their Genetic Mutations with Family Members

Surveys, Registries, Interviews
Survey and interview for people of Caribbean descent who tested positive for a genetic mutation linked to cancer.

Treatment of HER2-positive Colorectal Cancer as First Line Treatment in the Metastatic Setting

Treatment of HER2-positive Colorectal Cancer as First Line Treatment in the Metastatic Setting

Clinicaltrials.gov identifier:
NCT05253651

Treatment
People with HER2-positive colorectal cancer who have not yet received treatment in the metastatic setting

Study of Colorectal Cancer and Genetics in Hispanic and Latino People (ENLACE Study)

Study of Colorectal Cancer and Genetics in Hispanic and Latino People (ENLACE Study)

Treatment
Hispanic and Latino people diagnosed with colorectal cancer

Pancreatic Cancer Early Detection for People  at High Risk

Pancreatic Cancer Early Detection for People at High Risk

Clinicaltrials.gov identifier:
NCT04970056

Prevention
Registry and biobank for high risk people undergoing pancreatic cancer screening

My Best GI Eating Study

My Best GI Eating Study

Clinicaltrials.gov identifier:
NCT05396846

Prevention
Diet and weight loss study for people who are overweight and at increased risk of colorectal cancer

Registry to Promote Health Equity for People of African Ancestry with Breast or Prostate Cancer

Registry to Promote Health Equity for People of African Ancestry with Breast or Prostate Cancer

Clinicaltrials.gov identifier:
NCT05754658

Surveys, Registries, Interviews
This is a registry for people of African ancestry who have breast or prostate cancer

A Surveillance Program for Women at High Risk for Breast Cancer (CAPSBRACA)

A Surveillance Program for Women at High Risk for Breast Cancer (CAPSBRACA)

Clinicaltrials.gov identifier:
NCT03729115

Surveys, Registries, Interviews
Screening study for women at risk for breast cancer due to an inherited mutation or other risk factor

Nipple Sparing Mastectomy With Immediate Implant-Based Reconstruction for Women With Early-Stage Breast Cancer

Nipple Sparing Mastectomy With Immediate Implant-Based Reconstruction for Women With Early-Stage Breast Cancer

Clinicaltrials.gov identifier:
NCT05720039

Treatment
Nipple sparing mastectomy with reconstruction for women with early-stage breast cancer

Survey about Motivations and Barriers to Talking with Family Members about Inherited Cancer Risk

Survey about Motivations and Barriers to Talking with Family Members about Inherited Cancer Risk

Surveys, Registries, Interviews
Survey for people with an inherited gene mutation

Breastfeeding and Breast Cancer Screening in People at High Risk: Knowledge and Perspectives

Breastfeeding and Breast Cancer Screening in People at High Risk: Knowledge and Perspectives

Surveys, Registries, Interviews
Online survey for women with an ATM, BARD1, BRCA1, BRCA2, CDH1, CHEK2, PALB2, PTEN, RAD51C, RAD51D, STK11 or TP53 inherited mutation.

Tools To Be Fit: Tools to Improve Nutrition and Physical Activity for Cancer Survivors

Tools To Be Fit: Tools to Improve Nutrition and Physical Activity for Cancer Survivors

Clinicaltrials.gov identifier:
NCT05056077

Quality of Life
Bladder, breast, colon, endometrial, kidney (renal cell carcinoma), ovarian, prostate, or rectal cancer

Blood Markers of Early Pancreas Cancer

Blood Markers of Early Pancreas Cancer

Clinicaltrials.gov identifier:
NCT03568630

Prevention
Observational study for people with family history of pancreas cancer or an inherited mutation linked to pancreatic cancer risk

Helping Latinas Understand Their Risk for Breast Cancer and Get Breast Cancer Care

Helping Latinas Understand Their Risk for Breast Cancer and Get Breast Cancer Care

Clinicaltrials.gov identifier:
NCT05483283

Prevention
Latinas with a high risk of breast cancer

Bazedoxifene Plus Conjugated Estrogens for Hot Flashes in Women at High Risk for Breast Cancer

Bazedoxifene Plus Conjugated Estrogens for Hot Flashes in Women at High Risk for Breast Cancer

Clinicaltrials.gov identifier:
NCT04821141

Quality of Life
Women at high risk for breast cancer due to ATM, CDH1, CHEK2, NBN, NF1, PALB2, PTEN, STK11, P53 or PTEN mutation who have hot flashes

Inherited Cancer Registry (ICARE): Contribute to Research While Staying Informed

Inherited Cancer Registry (ICARE): Contribute to Research While Staying Informed

Clinicaltrials.gov identifier:
NCT03231891

Surveys, Registries, Interviews
People with an inherited mutation or cancer in the family

ELLIE's Project

ELLIE's Project

Quality of Life
A survey to gain a better understanding of the baseline lifestyle factors related to nutrition and physical activity in people with a hereditary cancer gene mutation.

If you would like a more in-depth search, visit our In-Depth Search Tool that searches for studies in FORCE’s database and in clinicaltrials.gov


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