Care for Transgender People
Care for Transgender People
Transgender, nonbinary and other gender diverse individuals with inherited mutations may have different risks and risk-management options than people with the same mutation. Although there has been little research on in transgender people, experts have begun to develop guidelines for transgender people with risk based on what is known.
risk in transgender people
Depending on the type of cancer, several factors play a role in cancer risk, including:
- sex assigned at birth
- gender-affirming surgery
- gender-affirming hormone therapy
- pregnancy
The cancers most likely to be effected by these factors include breast cancer and cancers related to the reproductive system. The table below lists these cancers and their related genes.
Cancer Type |
Genes |
Breast |
ATM, BARD1, BRCA1, BRCA2, CDH1, CHEK2, NBN, PALB2, PTEN, RAD51C, RAD51D, STK11, TP53 |
Endometrial |
BRCA1*, BRCA2*, EPCAM, MLH1, MSH2, MSH6, MUTYH, PALB2, PMS2, PTEN
|
Ovarian |
BRCA1, BRCA2, BRIP1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2*, RAD51C, RAD51D |
Prostate |
ATM, BRCA1, BRCA2, CHEK2, EPCAM, HOXB13, MLH1, MSH2, MSH6*, PMS2* |
*More research is needed to confirm a link between this gene and this type of cancer. |
|
It's important to find a healthcare team that is knowledgeable about special considerations related to risk in transgender people.
See below for more information on these topics.
In the News
Article : Breast cancer risk for transgender women with inherited mutations
There has been little research on breast cancer risk for...
Article : Breast cancer risk for transgender men with inherited mutations
There is little information related to the risks and treatment...