Our Featured Research Page lists cancer prevention, treatment and quality of life studies enrolling people with or at high risk for hereditary cancers. You can do a quick search to filter our featured studies by cancer type, study type or key word, or a more in-depth search through clinicaltrials.gov.
Featured Studies Results
Study Type: Prevention detection risk | Keyword: BRCA1
![Denosumab for Breast Cancer Risk Reduction in Women With an Inherited BRCA1 Mutation (The Breast Cancer Prevention Study)](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/634210d55013a.png)
Denosumab for Breast Cancer Risk Reduction in Women With an Inherited BRCA1 Mutation (The Breast Cancer Prevention Study)
Clinicaltrials.gov identifier:
NCT04711109
Prevention
Prevention study enrolling women ages 25-55 with a BRCA1 mutation
![A Study to Compare Two Surgical Procedures in Women with BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer (SOROCk)](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/5f8fb28eed3cd.jpg)
A Study to Compare Two Surgical Procedures in Women with BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer (SOROCk)
Clinicaltrials.gov identifier:
NCT04251052
Prevention
Ovarian cancer prevention for women with a BRCA1 mutation who still have their ovaries
![PATROL Study: Prostate Cancer Screening for People AT Genetic Risk FOr Aggressive Disease](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/65f0573c855b6.png)
PATROL Study: Prostate Cancer Screening for People AT Genetic Risk FOr Aggressive Disease
Clinicaltrials.gov identifier:
NCT04472338
Prevention
Screening study for people with a mutation linked to prostate cancer risk
![Pancreatic Cancer Screening Study (CAPS5)](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/637e23ab6bfcd.jpg)
Pancreatic Cancer Screening Study (CAPS5)
Clinicaltrials.gov identifier:
NCT02000089
Prevention
Screening study for people at high risk for pancreatic cancer
![Screening Study for Men at High Genetic Risk for Prostate Cancer](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/63dc53130e906.png)
Screening Study for Men at High Genetic Risk for Prostate Cancer
Clinicaltrials.gov identifier:
NCT03805919
Prevention
Prostate screening with MRI for men with Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) or a BRCA1, BRCA2, HOXB13, ATM, NBN, TP53, BRIP1, CHEK2, PALB2, RAD51C, RAD51D, or other mutation
![Testing a Vaccine for Preventing or Treating Triple-Negative Breast Cancer](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/65bba94822632.jpg)
Testing a Vaccine for Preventing or Treating Triple-Negative Breast Cancer
Clinicaltrials.gov identifier:
NCT04674306
Prevention
Prevention study for people with a BRCA1, BRCA2 or PALB2 inherited mutation who are planning to undergo risk-reducing mastectomy.
![Pancreatic Cancer Early Detection for People at High Risk](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/63af9bc21fafd.png)
Pancreatic Cancer Early Detection for People at High Risk
Clinicaltrials.gov identifier:
NCT04970056
Prevention
Registry and biobank for high risk people undergoing pancreatic cancer screening
![Screening in Men at High Risk of Developing Prostate Cancer](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/64f79bde16156.jpg)
Screening in Men at High Risk of Developing Prostate Cancer
Clinicaltrials.gov identifier:
NCT05608694
Prevention
Screening using MRI for men at risk of developing prostate cancer
![Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/631e917b99a69.jpg)
Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women
Clinicaltrials.gov identifier:
NCT05287451
Prevention
Prevention study for women at high risk for ovarian cancer
![Testing a Vaccine for Cancer Prevention in People with a BRCA1 or BRCA2 Mutation](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/621d1ebf8b463.jpg)
Testing a Vaccine for Cancer Prevention in People with a BRCA1 or BRCA2 Mutation
Clinicaltrials.gov identifier:
NCT04367675
Prevention
People with a BRCA1 or BRCA2 mutation
![Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/62393a8886b83.jpg)
Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)
Clinicaltrials.gov identifier:
NCT05129605
Prevention
People at high risk for prostate cancer due to an inherited mutation
![Blood Markers of Early Pancreas Cancer](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/60e9cec2c5b8d.jpg)
Blood Markers of Early Pancreas Cancer
Clinicaltrials.gov identifier:
NCT03568630
Prevention
Observational study for people with family history of pancreas cancer or an inherited mutation linked to pancreatic cancer risk.
![Helping People With a Genetic Mutation in BRCA1, BRCA2 or Lynch Syndrome Talk to Their Family Members About Their Risk for Cancer and Find the Best Way to Get Family Members Tested](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/650f62deb65b7.png)
Helping People With a Genetic Mutation in BRCA1, BRCA2 or Lynch Syndrome Talk to Their Family Members About Their Risk for Cancer and Find the Best Way to Get Family Members Tested
Clinicaltrials.gov identifier:
NCT05677048
Prevention
People with a genetic mutation in BRCA1, BRCA2 or Lynch syndrome who have relatives who have not been tested
![Developing a Test for the Detection of Ovarian Cancer](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/60d0f4ef4dbe4.jpg)
Developing a Test for the Detection of Ovarian Cancer
Clinicaltrials.gov identifier:
NCT04794322
Prevention
![Screening for Pancreatic Cancer in Patients with an Inherited BRCA1, BRCA2, PALB2 or ATM Mutation](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/603137590fdb0.jpg)
Screening for Pancreatic Cancer in Patients with an Inherited BRCA1, BRCA2, PALB2 or ATM Mutation
Clinicaltrials.gov identifier:
NCT02478892
Prevention
![Validating a Blood Test for Early Ovarian Cancer Detection in High-risk Women and Families](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/60d0fb3017767.png)
Validating a Blood Test for Early Ovarian Cancer Detection in High-risk Women and Families
Prevention
Screening study for women with a BRCA1, BRCA2, BRIP1, PALB2, RAD51C, RAD51D, PMS2, MLH1, MSH2, MSH6, or EPCAM mutation
![Blood Tests to Measure Ovarian Reserves in Women with a BRCA Mutation or Women Treated for Early-Stage Breast Cancer](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/60235874d96c1.jpg)
Blood Tests to Measure Ovarian Reserves in Women with a BRCA Mutation or Women Treated for Early-Stage Breast Cancer
Clinicaltrials.gov identifier:
NCT00823654
Prevention
![Pancreatic Cancer Screening Study for High Risk People](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/mri-pancreatic-cancer.jpg)
Pancreatic Cancer Screening Study for High Risk People
Clinicaltrials.gov identifier:
NCT03250078
Prevention
![Denosumab and Mammographic Density in Premenopausal Women With Dense Breasts (TRIDENT)](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/shutterstock_309289829.jpg)
Denosumab and Mammographic Density in Premenopausal Women With Dense Breasts (TRIDENT)
Clinicaltrials.gov identifier:
NCT04067726
Prevention
![Study for People with Unexpected Genetic Results](https://www.facingourrisk.org/cdn-cgi/image/width=400,height=300,format=webp/uploads/assets/research/images/GSRP.jpg)
Study for People with Unexpected Genetic Results
Clinicaltrials.gov identifier:
NCT02595957
Prevention
If you would like a more in-depth search, visit our In-Depth Search Tool that searches for studies in FORCE’s database and in clinicaltrials.gov