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Testing a Vaccine for Cancer Prevention in People with a BRCA1 or BRCA2 Mutation

Clinicaltrials.gov identifier:
NCT04367675

People with a BRCA1 or BRCA2 mutation

Testing a Vaccine for Cancer Prevention in People with a BRCA1 or BRCA2 Mutation

About the Study

NOTE: This study is no longer recruiting patients.

This study will look at a new vaccine known as INO-5401 used alone or combined with a second vaccine called INO-9012. The study will test if the vaccine is safe (without large side effects) and test a new way of giving vaccines. It will also test whether the vaccine activates the immune system. A goal of this research is to reduce cancer risk in people with a or mutation. Additional studies will be needed to learn if this vaccine approach lowers cancer risk in mutation carriers.

This Study is Open To:

NOTE: This study is no longer recruiting patients.

This Study is Not Open To:

NOTE: This study is no longer recruiting patients.