BRCA2 Inherited Mutations
Learn about the cancer risks and prevention and treatment options for people with an inherited BRCA2 mutationStay up to date on research and information
Sign Up for FORCE NewslettersInformation for People with an Inherited Mutation
People with an in have increased risk for certain cancers, including:
- breast
- ovarian
- pancreatic
People with a mutation have options for screening, prevention and treatment of . There are expert guidelines and clinical trials that focus on:
- screening and early detection
- risk-reduction
- treatment
The expert guidelines are updated every year based the results of new research.
There may be other medical concerns for people with a mutation, including a rare childhood disease known as Fanconi anemia which can happen in people who inherit a mutation in both copies of their gene.
Each of these topics is outlined in more detail in the sections highlighted below.
More Information on Mutations
Cancer Risks
Cancer risk estimates are updated based on the latest research. Read about the lifetime risk for different cancers in people with inherited mutations.
Risk Management Options
Read about the latest expert guidelines for cancer screening and prevention for people with a mutation. Learn about research studies enrolling high-risk patients.
Cancer Treatment Options
Tumor testing and genetic testing can provide additional clues about which treatments may work best for your cancer. People who test positive for a mutation may have additional treatment or clinical trial options available to them.
Other Considerations
People who inherit a mutation in both copies of their gene—one from each parent—have a rare disease known as Fanconi anemia. Learn additional information about inherited mutations.
Participate in Prevention Research
The screening and prevention studies below are enrolling people with mutations. To search for more studies, visit our Search and Enroll Tool.
Participate in Treatment Research
The treatment studies below are enrolling people with mutations. To search for more studies, visit our Search and Enroll Tool.
Watch Our Webinar for People with Mutations
Webinar: Cancer Risks, Screening and Prevention for People with BRCA1 or BRCA2 Mutations