Endometrial Cancer Treatment
Learn about national guidelines and treatment options for people with hereditary endometrial cancer.Stay up to date on research and information
Sign Up for FORCE NewslettersEndometrial Cancer Treatment
Treatment for endometrial cancer depends on the stage and type of the disease based on pathology results. Tumor biomarker testing and genetic testing can provide additional clues about which treatments may work best against your cancer. For people with metastatic or advanced cancer, these additional tests are usually recommended.
Standard treatment may include a combination of surgery, chemotherapy, radiation and hormone therapy. Some people may also benefit from treatment with immunotherapies or targeted therapies. Clinical trials may be available for any stage of cancer.
Which genes are linked to hereditary endometrial cancer?
About 10 percent of people diagnosed with endometrial cancer will test positive for an inherited mutation. People with an inherited mutation in the genes below may have different treatment recommendations or options.
Make sure that you receive a copy of your cancer test results, including your pathology report and your cancer stage. Ask your doctor to explain your diagnosis, test results and treatment options in terms that you can understand. This will allow you to work with your doctor to choose the treatment plan that is right for you.
See below for more information on each of these endometrial cancer treatment topics.
In the News
Study: Immunotherapy improves outcomes of advanced endometrial cancer
Standard treatment for advanced endometrial cancer may soon change. A study found that people with advanced or recurrent endometrial cancer who received immunotherapy with chemotherapy had better outcomes than those who had chemotherapy alone. (Posted...
More Information on Endometrial Cancer Treatment
Stages & Subtypes
Treatment for endometrial cancer depends on the stage and type based on pathology results. Learn how doctors determine the stage and subtype of endometrial cancers.
Standard Therapies
Treatment for endometrial cancer often includes a combination of surgery, chemotherapy, radiation and hormone therapy. Learn more about these types of treatments.
Biomarker Testing
Tumor biomarker testing and genetic testing can provide additional clues about which treatments may work best against your cancer.
Targeted & Immunotherapies
Targeted therapies are designed to attack or kill cancer cells, while sparing normal cells as much as possible. Immunotherapies help the body’s immune system detect and attack cancer cells.
Genetic Testing for Inherited Mutations
There are national guidelines that outline who should consider genetic counseling and testing for an inherited mutation linked to cancer.
Participate in Endometrial Cancer Treatment Research
Below are some of our featured research studies looking at new treatments for endometrial cancer treatment. To search for more studies, visit our Search and Enroll Tool.
Clinicaltrials.gov identifier:
NCT05572684
A Study of Targeted Therapies for Patients With Recurrent Endometrial Cancer
Clinicaltrials.gov identifier:
NCT04486352
Testing an Immunotherapy in Patients with Advanced Solid Tumors
Clinicaltrials.gov identifier:
NCT02628067
Clinicaltrials.gov identifier:
NCT02693535
Testing Immunotherapy Treatments for Recurrent Endometrial Cancer
Clinicaltrials.gov identifier:
NCT05112601
Clinicaltrials.gov identifier:
NCT04463771