Other Considerations for People with Inherited CDK4 Mutations

The risk for cancer in people with an inherited CDK4 mutation begins at a young age. Parents with a mutation should speak with a genetics expert about the best timing for testing children.

Parents with a mutation have a 50 percent chance of passing their mutation on to each of their children. There are options using assisted reproduction technology and preimplantation genetic diagnosis for parents to select embryos that are free of inherited CDK4 mutations.