Hereditary Pancreatic Cancer Risk
Pancreatic Cancer Risk
What is pancreatic cancer?
The pancreas is an organ in the abdomen that helps with digestion of food and controlling sugar levels in the blood.
There are two main groups of pancreatic cancer based on the type of cells where the cancer developed. These cancers behave differently and are treated differently.
- The most common type of pancreatic cancers are called exocrine pancreatic cancers. This group includes pancreatic adenocarcinomas. These cancers tend to be very aggressive.
- Pancreatic neuroendocrine tumors (PNETs) are much less common. These cancers may be less aggressive and slower growing than pancreatic adenocarcinomas.
Who is at risk for pancreatic cancer?
Everyone is at risk for pancreatic cancer; the risk increases with age.
Factors that affect pancreatic cancer risk include:
- personal and family history of cancer
- inherited mutations linked to pancreatic cancer risk
- type 2 diabetes
- personal history of chronic pancreatitis
- lifestyle and habits including diet, weight, exercise, smoking and alcohol consumption
In the News
Despite national guidelines recommending genetic testing, less than 10 percent of eligible patients had genetic testing within two years after their cancer diagnosis. Among those who had testing, 10-30 percent...
Is pancreatic cancer hereditary?
About 10% of people with pancreatic cancer have an linked to cancer risk. Genetic counseling and testing can help people learn if they are at high risk. Mutations in the genes below increase pancreatic cancer risk and can cause cancer to run in families.
Other, rare inherited mutations may also increase risk.
Learn about pancreatic cancer risk management and treatment
Learn about Risk Management Options
National expert guidelines for pancreatic cancer risk management vary based on gene mutation and other factors that affect risk. Click on the button below to learn more about these guidelines.
Learn about Treatment Options
People diagnosed with pancreatic cancer may have different treatment options based on , type, and genetic and results. Click on the button below to learn more about these treatment options.