FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you.
XRAY is a reliable source of hereditary cancer research-related news and information.
Learn more about the XRAY program
All XRAYs
Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Human Research
Study : Yearly breast MRI screening improves outcomes for women with inherited BRCA mutations
Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Human Research
Most relevant for: People with a BRCA1 or BRCA2 mutation who are considering breast MRI screening
An international research study of yearly breast MRI screening among women with BRCA1 and BRCA2 gene mutations found that BRCA1 carriers who had MRI screenings were less likely to die of breast cancer than those who did not. Additional studies with more BRCA2 mutation carriers are needed to determine if yearly breast MRIs reduce deaths from breast cancer in this group. (Posted 6/24/24)
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Relevance: Medium-High
Strength of Science: High
Research Timeline: Post Approval
Update : Targeted therapy for early-stage HER2-positive breast cancer continues to show benefit
Relevance: Medium-High
Strength of Science: High
Research Timeline: Post Approval
Most relevant for: People with early-stage HER2-postive breast cancer
People with early-stage HER2-positive breast cancer benefit from targeted therapy. This update includes new data on survival and the length of time without cancer returning. (Posted 6/20/24)
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Update : News from the FDA: New ovarian cancer treatment and imaging drug
Most relevant for: People with ovarian cancer.
The FDA recently approved a new treatment for some people with ovarian cancer. The FDA also approved a new imaging drug that can help surgeons find and remove ovarian cancer. (Posted 5/30/24)
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Relevance: High
Strength of Science: High
Research Timeline: Post Approval
Study : Ovary removal reduces risk of death from any cause in people with BRCA mutations
Relevance: High
Strength of Science: High
Research Timeline: Post Approval
Most relevant for: People who have had a risk reducing bilateral oophorectomy
People who test positive for an inherited BRCA1 or BRCA2 mutation can reduce their risk of ovarian cancer by having both ovaries and fallopian tubes removed. A study published in 2024 found an added benefit of this surgery – a lower risk of death from any cause by age 75. (Posted 5/23/24)
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Relevance: Medium
Personal Story : Living a full life with Li-Fraumeni syndrome
Relevance: Medium
Most relevant for: People with Li-Fraumeni syndrome
This XRAY review is about a five-time cancer survivor who has an inherited mutation in the TP53 gene. People with inherited mutations in TP53 have Li-Fraumeni syndrome, which is linked to a very high lifetime risk for many types of cancer. Here we share his inspiring story and provide more information on Li-Fraumeni syndrome. (Posted 4/16/24)
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Update : News from the FDA - Two new metastatic colorectal cancer treatments
Most relevant for: People with colorectal cancer
The FDA recently approved two new treatments for metastatic colorectal cancer. (Posted 3/22/24)
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Topic : Progress in the treatment of triple-negative breast cancer
Most relevant for: People with triple-negative breast cancer
During the December 2023 San Antonio Breast Cancer Symposium, Dr. Melinda Telli presented a summary of research that has led to better treatments for triple-negative breast cancer (TNBC). These treatments now include drugs called targeted therapies and immunotherapies for both early and late stages of TNBC. (Posted 3/19/24)
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Relevance: High
Strength of Science: High
Research Timeline: Post Approval
Study : Genetic testing among people with cancer can find mutations that may affect treatment and prevention
Relevance: High
Strength of Science: High
Research Timeline: Post Approval
Most relevant for: People diagnosed with cancer who have not yet had genetic testing
Despite national guidelines recommending genetic testing, less than 10 percent of eligible patients had genetic testing within two years after their cancer diagnosis. Among those who had testing, 10-30 percent had an inherited mutation that could affect their medical care. (Posted 3/15/2024)
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Relevance: Medium
Update : News from the FDA– new breast cancer treatment, thermography warning and implant screening updates
Relevance: Medium
Most relevant for: People with HR-positive and HER2-negative metastatic breast cancer. People with silicone breast implants. People considering thermography screening
This XRAY review is a summary of FDA breast cancer updates from July to December 2023. This includes a new drug approval and two consumer updates. (Posted 2/21/24)
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Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Study : Estrogen without progesterone for hormone replacement may lower breast cancer risk
Relevance: Medium-High
Strength of Science: Medium-High
Research Timeline: Post Approval
Most relevant for: Postmenopausal people on hormone replacement therapy
Women with average breast cancer risk who took estrogen without progesterone after menopause had lower rates of breast cancer than those who did not take any hormone replacement. This finding comes from studies looking at the safety of the use of estrogen alone as hormone replacement therapy. (Posted 2/13/24)
Este artículo está disponible en español.
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