Prostate Cancer Risk Management
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All men (people assigned male at birth) are at risk for cancer and the risk increases with age. The average lifetime risk for cancer is 12 percent. This means that 1 out of every 8 men will get cancer in their lifetime.
An in one of the genes listed below increases the risk for cancer.
Genes with Prostate Cancer Risk-Management Guidelines |
*In addition to increasing lifetime risk for prostate cancer, BRCA1 and BRCA2 and HOXB13 also increase risk for more aggressive, metastatic disease. ** More research is needed to confirm a link between prostate cancer and an inherited mutation in this gene. |
Genetic counseling and testing can help you learn if you have an in one of these genes. There are different expert guidelines for cancer screening, which are based on your level of risk. Read below for more information about different screening options. Speak with your healthcare provider to decide on a risk-management plan and schedule that is right for you.
In the News
Study : Genes linked to aggressive prostate cancer
Previous research has linked some inherited mutations to prostate cancer risk. This study found a link to additional genes that should be added to prostate cancer gene panel tests. The study also looked at which...
Risk-Management Options
Cancer Screening Options
There are options for early detection of cancer. The benefits and risks of screening vary depending on your situation. Read more about your options here.
Cancer Screening Guidelines
There are several different expert guidelines for cancer screening for average-risk and high-risk people that differ in their recommendations. Read more about these guidelines here.
Participate in Cancer Prevention Research
Below are some of our featured research studies looking at new ways to screen for cancer. To search for more studies, visit our Search and Enroll Tool.
PATROL Study: Prostate Cancer Screening for People AT Genetic Risk FOr Aggressive Disease
Clinicaltrials.gov identifier:
NCT04472338
Screening Study for Men at High Genetic Risk for Prostate Cancer
Clinicaltrials.gov identifier:
NCT03805919
Screening in Men at High Risk of Developing Prostate Cancer
Clinicaltrials.gov identifier:
NCT05608694
Testing a Vaccine for Cancer Prevention in People with a BRCA1 or BRCA2 Mutation
Clinicaltrials.gov identifier:
NCT04367675
Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)
Clinicaltrials.gov identifier:
NCT05129605
