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Education > XRAY > Hereditary Cancer Risk

FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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Hereditary Cancer Risk

101 through 110 of 136

Relevance: Medium

Quality of Writing: Medium-High

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Article : Mixed reviews of at-home genetic testing

Relevance: Medium

Quality of Writing: Medium-High

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Most relevant for: People who are considering or have had direct-to-consumer testing

National guidelines recommend that patients meet with a genetics expert before undergoing genetic testing for cancer risk. Genetic counseling can help patients decide whether genetic testing is right for them and order the most appropriate test. Once test results are available, genetics experts also help patients understand their results. Over the last decade, the popularity of direct-to-consumer (DTC) genetic testing, such as 23andMe has grown. Some genetic tests are marketed to consumers on television, in print advertisements, and on the Internet. These “at-home” genetic tests give people direct access to their genetic information without first involving a healthcare provider in the process. A recent report outlines the benefits and limitations of DTC genetic testing. (10/20/17)

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Relevance: Medium-High

Strength of Science: Medium

Study : Beauty and the breast: hair product use and breast cancer risk

Relevance: Medium-High

Strength of Science: Medium

Most relevant for: Women who use hair products who are concerned about their risk for breast cancer

Past studies using mostly animal models showed a link between use of hair products (dyes, straighteners and relaxers) and increased risk of certain cancers. In this study, researchers looked at data on hair product use among African-American (AA) and White women to see if certain types of hair products increased breast cancer risk, and how that risk might differ between race and breast cancer hormone status. (9/27/2017)

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Relevance: Medium-High

Quality of Writing: Medium-High

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Article : Can lifestyle changes impact breast cancer risk?

Relevance: Medium-High

Quality of Writing: Medium-High

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Most relevant for: Any woman concerned about her risk for breast cancer

A recent New York Times article shared how “adopting protective living habits”  could help keep breast cancer “at bay”.  While many of these lifestyle changes and strategies like not smoking, avoiding weight gain, reducing alcohol consumption, eating a heart-healthy diet, and increasing physical activity have been shown to reduce breast cancer risk, there are other risk factors that one cannot control such as having a BRCA or other mutation that significantly increases breast cancer risk. Importantly, no one strategy has been proven to totally eliminate breast cancer risk. However many of these approaches have overall health benefits. (9/21/2017)

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Relevance: Medium-High

Strength of Science: Medium

Research Timeline: Post Approval

Study : Does aspirin lower a woman’s breast cancer risk?

Relevance: Medium-High

Strength of Science: Medium

Research Timeline: Post Approval

Most relevant for: Women at average risk for breast cancer

Women who take aspirin regularly may have a reduced risk of breast cancer. However, previous studies have reported mixed results. Few of these studies have looked at whether this potential benefit of aspirin is linked to specific types of breast cancer. This study found a small reduction in breast cancer risk for women who took a low-dose aspirin at least three times per week, but only for one subtype of breast cancer. Women who took aspirin were less likely to develop ER/PR-positive, Her2- negative breast cancer, the most common type of breast cancer. This study found no breast cancer risk reduction for women who used regular-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDS). (8/29/17)

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Relevance: Medium-High

Quality of Writing: High

Article : Parents face challenges when deciding the best time to tell children that they may be at high risk for cancer

Relevance: Medium-High

Quality of Writing: High

Most relevant for: Parents who have an inherited gene mutation

When certain types of cancers run in families, genetic testing can determine whether the cause is hereditary. Genetic testing can help family members understand their cancer risk and make medical decisions to stay healthy. A test result can provide significant insight, but it also creates challenges for parents, because gene mutations that cause hereditary cancers can be passed from mothers and fathers to sons and daughters. People with these mutations must make difficult decisions about when to tell their children that they too may have inherited the mutation. (8/22/2017)

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Relevance: Medium

Strength of Science: Medium

Study : Breast cancer rates are rapidly increasing among Asian women in California

Relevance: Medium

Strength of Science: Medium

Most relevant for: Asian American women

The majority of racial groups in the United States have seen declines in breast cancer rates. However, this study provides new insights into the patterns of breast cancer rates in Asian American subgroups in California. Using 26 years of data, this research found that breast cancer is rapidly increasing among this population, contrasting to a decline in rates among non-Hispanic white women in California and nationwide. (8/15/17)

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Relevance: Medium

Strength of Science: Medium

Research Timeline: Post Approval

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Study : Do physicians recommend breast cancer screenings based on guidelines?

Relevance: Medium

Strength of Science: Medium

Research Timeline: Post Approval

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Most relevant for: Women at average risk for breast cancer

Several guidelines help physicians decide when a woman should begin screening for breast cancer and how often she should be screened. However, are these guidelines put into use in the clinic? (8/8/17)

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Relevance: Medium-Low

Strength of Science: Medium-Low

Research Timeline: Animal Studies

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Article : Report on vaccines to prevent hereditary cancer

Relevance: Medium-Low

Strength of Science: Medium-Low

Research Timeline: Animal Studies

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Most relevant for: High risk women who have not had breast cancer

On 05/30/2017, Good Morning America aired a segment entitled “Can a vaccine help prevent breast cancer at its earliest stages?” The story outlines the need for cancer prevention and hints at early research into a cancer vaccine. (8/1/17)

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Relevance: High

Strength of Science: High

Research Timeline: Post Approval

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Study : New cancer risk estimates for BRCA1/2 mutation carriers

Relevance: High

Strength of Science: High

Research Timeline: Post Approval

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Most relevant for: Women with an inherited mutation in BRCA1 or BRCA2

Cancer risk estimates for BRCA1 and BRCA2 mutation carriers are important because they impact patient decision-making. Until now, almost all risk estimates for mutation carriers were based on results of retrospective studies that looked back on mutation carriers who had cancer. This new study is prospective—it followed almost 10,000 BRCA mutation carriers without cancer to see if or when they developed breast or ovarian cancer. The cancer risk estimates of this study may be more accurate because it followed mutation carriers who did not have cancer over time. (7/28/17)

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Relevance: Medium-High

Strength of Science: Medium

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Study : Diet during teen years and early adulthood is linked to breast cancer risk

Relevance: Medium-High

Strength of Science: Medium

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Most relevant for: Adolescent and young adult women

During teen years, breast tissue grows rapidly in young girls and is more likely to be harmed by substances that are known to cause cancer. Few studies have looked at the relationship between diet during puberty and breast cancer risk. This study looks at how a woman’s diet during their teenage years and early adulthood is associated with breast cancer development later in life. (6/30/17)

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