The DETECT Study: Detecting Endometrial Cancer in Tampons

https://www.facingourrisk.org/research-clinical-trials/study/306/the-detect-study-detecting-endometrial-cancer-in-tampons

Clinicaltrials.gov identifier:
NCT03538665 (https://clinicaltrials.gov/show/NCT03538665)

Prevention
Early detection of endometrial cancer in women over 45 years of age who are undergoing hysterectomy surgery at the University of Alabama

Study Contact Information:

For additional information, please contact:

Rebecca C Arend, MD by phone at (917) 532-5370 or Email: [email protected]

Megan A Clarke-Corso, Ph.D. by phone at (240) 276-7823 or Email: [email protected]

About the Study

Women over 45 years of age who are scheduled for a hysterectomy for endometrial cancer, endometrial cancer precursors, or benign conditions at the University of Alabama’s Division of Gynecological Oncology will use vaginal tampons to test whether samples collected on the tampon can detect endometrial cancer.

What the Study Involves

Prior to surgery, participants will be given a 10-question survey to see if they find tampon sampling acceptable.

They will then put a tampon in their vagina at least 30 minutes before surgery. Their tampons will be collected during the surgery. A small piece of uterine tissue will be removed during surgery. Researchers will study both tampon and tissue samples.

Researchers will follow the participant’s medical records for up to 3 years.

Study Site

Alabama
University of Alabama
Birmingham, Alabama, 35233
Contact: Warner Huh (205) 934-4986 or [email protected]

Lead Researcher

Rebecca C. Arend, MD,University of Alabama at Birmingham

This Study is Open To:

Women, 45 years and older, who meet the following criteria:

Will undergo hysterectomy (surgery to remove the uterus) for endometrial cancer, precursors or atypical hyperplasia (early changes that can lead to endometrial cancer), or benign condition including fibroids, polyps, endometrial hyperplasia, adenomyosis, and normal endometrium at the University of Alabama Birmingham Division of Gynecologic Oncology
Have the ability to understand the study and give informed consent

This Study is Not Open To:

Women under 45 years old
Pregnant women
Men

About FORCE

FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.