Lifetime cancer risks in people with an inherited mutation in CDH1
https://www.facingourrisk.org/XRAY/lifetime-cancer-risks-among-CDH1-carriers
Full article: https://jamanetwork.com/journals/jama/article-abstract/2820241
This study looked at the lifetime risks of stomach and breast cancer in families with a known CDH1 mutation. Results from the study suggest that for some CDH1 mutation carriers lifetime stomach cancer risk is lower than previous research has shown. Additionally, study results show that the lifetime risk of breast cancer is similar to previous lifetime risk estimates in women with mutations in this gene. (Posted 12/10/24)
Questions To Ask Your Health Care Provider
- I have a family or personal history of stomach cancer or lobular breast cancer. Should I consider genetic testing?
- I have a CDH1 mutation. What are my risks for cancer?
- Have you followed many people with CDH1 mutations?
- I have a CDH1 mutation. What are the benefits and downsides of risk-reducing gastrectomy? Of surveillance?
- I have a CDH1 mutation. What are my options for managing my risk for stomach cancer and breast cancer?
About FORCE
FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.